Bilbao transformed itself from a gritty industrial port into a design capital, anchored by Frank Gehry's titanium-clad Guggenheim Museum. The Basque city pairs that architectural wow with a characterful old town, a world-renowned pintxos (Basque tapas) scene, and easy access to the elegant beach resort of San Sebastián. Ships dock at Getxo, a short ride from the city.
Do the Guggenheim, but don't skip the Casco Viejo — Bilbao's soul is in its pintxos bars, where you graze counter to counter. If you'd rather have a beach-and-glamour day, San Sebastián is an hour away and worth the trip.
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