Royal Caribbean

Serenade of the Seas — Panama Canal Eastward Cruise

15 nights · from San Diego · 1 upcoming sailing

From $1,976/pp

About this itinerary

The 15-Night Panama Canal Eastward Cruise sails on Serenade of the Seas (Royal Caribbean) round-trip from San Diego. Below are the next upcoming departures with the lowest cabin fare we’re currently tracking for each — prices update daily, so check back to catch a drop.

Ports of call
📍 San Diego📍 Day at Sea📍 Day at Sea📍 Puerto Vallarta📍 Day at Sea📍 Day at Sea📍 Puerto Quetzal📍 Day at Sea📍 Puntarenas📍 Day at Sea📍 Panama Canal (Cruising)📍 Cartagena📍 Day at Sea📍 George Town📍 Day at Sea📍 Tampa
Upcoming Panama Canal Eastward Cruise sailings
1 future departure on Serenade of the Seas
October 7, 2027
15 nights · San Diego
From $1,976/pp
More itineraries on Serenade of the Seas
Alaska Inside Passage Cruise →Western Caribbean Cruise →Ensenada Cruise →Catalina & Ensenada Cruise →Ensenada, Cabo & La Paz Cruise →Cabo, Mazatlan & La Paz Cruise →Pacific Coastal Cruise →Ensenada, Cabo & Mazatlan Cruise →
← All Serenade of the Seas itineraries & ship guide